ACOX1 Antibody(C-term)
Cat.#: T0816
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q15067
Mol Weight: 74kDa
Size: 100ug

Description
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Recommended Applications
WB, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human

Products Data

Western blot analysis of ACOX1 (arrow) using rabbit polyclonal ACOX1 Antibody (C-term) (RB04651). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACOX1 gene (Lane 2) (Origene Technologies).

Specificity
This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 631~660 amino acids from the C-terminal region of human ACOX1.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Alternative Names
ACOX1 antibody, ACOX antibody, MGC1198 antibody, PALMCOX antibody, SCOX antibody, Peroxisomal acyl-coenzyme A oxidase 1 antibody, Palmitoyl-CoA oxidase antibody, Straight-chain acyl-CoA oxidase antibody

Description References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Chu, R., et al., J. Biol. Chem. 270(9):4908-4915 (1995).
Aoyama, T., et al., Biochem. Biophys. Res. Commun. 198(3):1113-1118 (1994).
Fournier, B., et al., J. Clin. Invest. 94(2):526-531 (1994).
Varanasi, U., et al., Proc. Natl. Acad. Sci. U.S.A. 91(8):3107-3111 (1994).

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途