ADAMTS18 Antibody(C-term)
Cat.#: T3553
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q8TE60
Mol Weight: 135kDa
Size: 100ug

Description
ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor.

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:100~500
IHC: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human, Mouse

Products Data 

 

Western blot analysis of ADAMTS18 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). ADAMTS18 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human brain tissue reacted with ADAMTS18 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specificity
This ADAMTS18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1073~1103 amino acids from the C-terminal region of human ADAMTS18.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Alternative Names
ADAMTS18 antibody, ADAMTS21 antibody, A disintegrin and metalloproteinase with thrombospondin motifs 18 antibody, antibody

Description References
Zeng,W., et.al., Biochim. Biophys. Acta 1760 (3), 517-524 (2006)
Jin,H., et.al., Oncogene 26 (53), 7490-7498 (2007)

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途