AK2 Antibody(N-term)
Cat.#: T3054
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P54819
Mol Weight: 26kDa
Size: 100ug

Description
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:100~500
IHC: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human, Mouse

Products Data 

 

The anti-AK2 Pab is used in Western blot to detect AK2 in mouse kidney tissue lysate.
Western blot analysis of anti-AK2 Antibody (N-term) in CEM cell line lysates (35ug/lane). AK2(arrow) was detected using the purified Pab.

Specificity
This AK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~31 amino acids from the N-terminal region of human AK2.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Alternative Names
AK2 antibody, ADK2 antibody, AK 2 antibody, Adenylate kinase 2, mitochondrial antibody, ATP-AMP transphosphorylase 2 antibody

Description References
Noma, T., et al., Biochim. Biophys. Acta 1395(1):34-39 (1998).
Lee, Y., et al., J. Biochem. 123(1):47-54 (1998).
Lee, Y., et al., Biochem. Mol. Biol. Int. 39(4):833-842 (1996).
Bruns, G.A., et al., Biochem. Genet. 15 (5-6), 477-486 (1977). 

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途