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MouseAntiHumanGlycogensynthasekinase-3beta(GSK3B)

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Catalogue Number ANT-404
Synonyms GSK3B, Glycogen synthase kinase-3 beta, GSK-3 beta.
Type Mouse Anti Human Monoclonal.
Introduction GSK3B is a serine-threonine kinase that belongs to the glycogen synthase kinase subfamily. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in the GSK3B gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of the GSK3B gene may be significant to the pathogenesis of Alzheimer disease.
Clone P1F7AT.
Immunogen Anti-human GSK3B mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GSK3B amino acids 341-420 purified from E. coli.
Ig Subclass Mouse IgG1 heavy chain and κ light chain.
Purification Method GSK3B antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life 12 months at -20°C. 1 month at 4°C.
Applications GSK3B antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 3,000. Recommended starting dilution is 1:2,000.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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