AP2-alpha(TFAP2A)antibody
Cat.#: 3154-1
Rabbit Monoclonal Antibody
Clone ID: EPR2688(2)
Swiss Prot: P05549
Mol Weight: 48kDa
Size: 100ul

Description
AP2-alpha is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. This protein functions as either a homodimer or as a heterodimer with similar family members. AP2-alpha activates some proteins while inhibiting others. Defects in AP2-alpha are a cause of branchiooculofacial syndrome (BOFS).

Recommended Applications
WB, IHC, ICC, IP

Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:250 - 500
IP: 1:10 - 100

Species Reactivity
Human, Mouse, Rat

Mouse cross reactivity tested by western blot and IHC
Rat cross reactivity tested by western blot only

Products Data  

 

Western blot analysis on (A) HeLa, (B) JAR, and (C) Raw264.7 cell lysates using anti-AP2-alpha RabMAb (cat. #3154-1).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-AP2-alpha RabMAb (cat. #3154-1).
Immunofluorescent staining of HeLa cells using anti-AP2-alpha RabMAb (cat. #3154-1).

Specificity
A synthetic peptide corresponding to residues in human AP2-alpha was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
TFAP2A antibody, AP-2 antibody, AP-2alpha antibody, AP2TF antibody, BOFS antibody, FLJ51761 antibody, TFAP2 antibody, Transcription factor AP-2-alpha antibody, AP-2 transcription factor antibody, Activating enhancer-binding protein 2-alpha antibody, Activator protein 2 antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.

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