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20SProteasomealpha2antibody

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询价
产品介绍

20S Proteasome alpha2 antibody
Cat.#: S1136
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P25787
Mol Weight: 25.9kDa
Size: 100ug

Description
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq]

Recommended Applications
WB, ICC

Applications and Recommended Dilution Factors
WB: 1:500-1:3000
ICC: 1:100-1:200

Species Reactivity
Human

Other species have not been tested

Products Data


Sample(30ug of whole cell lysate)
A: H1299
B: HeLa S3
C: Hep G2
D: MOLT4
E: Raji
12% SDS PAGE
diluted at 1:1000

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 226 of 20S Proteasome alpha2

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
PSMA2 antibody, HC3 antibody, MU antibody, PMSA2 antibody, PSC2 antibody, Proteasome subunit alpha type-2 antibody, Macropain subunit C3 antibody, Multicatalytic endopeptidase complex subunit C3 antibody, Proteasome component C3 antibody 

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途