AKT3 Antibody(N-term)
Cat.#: T1934
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q9Y243
Mol Weight: 56kDa
Size: 100ug

Description
AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
IHC: 1:50-100
ELISA: 1:1,000

Species Reactivity
Human

Products Data 

 

Western blot analysis of anti-AKT3 Antibody (N-term) Pab in Hela cell line lysates (35ug/lane). AKT3(arrow) was detected using the purified Pab (1:30 dilution).
Western blot analysis of anti-AKT3 Antibody (N-term) Pab (RB11641) in 293 cell line lysates transiently transfected with the AKT3 gene (2ug/lane). AKT3(arrow) was detected using the purified Pab (1:60 dilution).

Specificity
This AKT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97~127 amino acids from the N-terminal region of human AKT3 Antibody.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Alternative Names
AKT3 antibody, DKFZp434N0250 antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, RAC-gamma serine/threonine-protein kinase antibody, RAC-PK-gamma antibody, STK-2 antibody

Description References
Xu, Z., et al., Biochem. Biophys. Res. Commun. 312(2):388-396 (2003).
Tiwari, G., et al., Mol. Cancer Res. 1(6):475-484 (2003).
Brozinick, J.T. Jr., et al., Diabetes 52(4):935-941 (2003).
Deregibus, M.C., et al., J. Biol. Chem. 277(28):25195-25202 (2002).
Brodbeck, D., et al., J. Biol. Chem. 276(31):29550-29558 (2001).

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途