ALDH3A1 Antibody(N-term)
Cat.#: T2801
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P30838
Mol Weight: 50kDa
Size: 100ug

Description
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. The enzyme is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea.

Recommended Applications
WB, IHC, FC, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
IHC: 1:50~100
FC: 1:10~50
ELISA: 1:1,000

Species Reactivity
Human

Products Data

 

Western blot analysis of ALDH3A1 (arrow) using rabbit polyclonal ALDH3A1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH3A1 gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with ALDH3A1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specificity
This ALDH3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77~106 amino acids from the N-terminal region of human ALDH3A1.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Alternative Names
ALDH3A1 antibody, ALDH3 antibody, ALDHIII antibody, MGC10406 antibody, Aldehyde dehydrogenase, dimeric NADP-preferring antibody, ALDHIII antibody, Aldehyde dehydrogenase 3 antibody, Aldehyde dehydrogenase family 3 member A1 antibody

Description References
Glatt,H., Arch. Biochem. Biophys. 477 (2), 196-205 (2008)
Ekhart,C., Pharmacogenet. Genomics 18 (6), 515-523 (2008)
Giebultowicz,J., Acta Pol Pharm 65 (1), 81-84 (2008) 

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途