正品|Ketoconazole;酮康唑;K1003;CAS号:65277-42-1现货原装,其它生化试剂

产地：usa
货号：K1003
名称：Ketoconazole
别名: (±)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine
CAS号: 65277-42-1
分子量: 531.43
Biochem/physiol Actions
Antifungal agent
First generation antifungal azole. Mode of action: Inhibits cytochrome P450-dependent 14α-demethylase, which is critical to ergosterol biosynthesis. The accumulated 14α-methylated sterols change the membrane structure of sensitive fungi, resulting in an altered cell membrane permeability.
相关类型 Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Bioactive Small Molecules,
Cell Biology, Cell Signaling Enzymes, Chemical Structure Class, Core Bioreagents, Imidazoles, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, Inhibitors, K, Research Essentials, Spectrum of Activity, Substrates, Xenobiotics and Drug Metabolism
more...
Quality Level PREMIUM
assay ≥98% (TLC)
storage temp. 2-8°C
Gene Information Research your gene in Your Favorite Gene powered by Ingenuity
human ... ABCB1(5243), CYP11B1(1584), CYP11B2(1585), CYP17A1(1586), CYP19A1(1588), CYP1A2(1544), CYP24A1(1591), CYP26A1(1592), CYP3A4(1576), CYP51A1(1595), KCNH1(3756)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Alox5(25290), Cyp17a1(25146), Cyp51(25427), Cyp7a1(25428)

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