原装Blexane;Blenoxane;Bleo;B5507正品现货
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
Sigma | 暂无 | 暂无 | 现货 |
产地:usa
货号:B5507
名称:Bleomycin sulfate from Streptomyces verticillus
别名: Blenoxane, Bleo, Blexane
相关类型 Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antifungal,
Antineoplastic and Immunosuppressive Antibiotics, Antitumor Agents, Apoptosis and Cell Cycle, B, Bioactive Small Molecules, Cancer Research, Cell Biology, Chemical Structure Class, DNA Modification / Repair, DNA Synthesis Inhibitors, DNA metabolism, Genetic Marker Selection, Glycopeptides, Interferes with DNA Synthesis, Mechanism of Action, Spectrum of Activity
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form crystalline
color white
solubility H2O: soluble20 mg/mL
cation traces Cu: <0.1%
storage temp. 2-8°C
Application
Recommended for use as a selection agent at 10-100 μg/ml.
Other Notes
A mixture of bleomycin sulfate salts
Biochem/physiol Actions
An antineoplastic antibiotic isolated from Streptomyces verticillus. Binds to DNA, inhibits DNA synthesis and causes DNA scissions at specific base sequences. Needs to bind oxygen and a metal ion such as copper or iron to cleave DNA. Highly selective cleavage of RNA. Inducer and regulator of apoptosis in a variety of cells. Inhibits tumor angiogenesis.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途