Product Specification
Source/Host: The synthetic UBA domain is coupled to derivatised-agarose at a concentration of 2 mg protein/mL of settled resin.
Long Term Storage: +4°C
Miscellaneous/General: A ubiquitin-associated domain (UBA) has been predicted at the C-terminus of NBR1. It has been shown that UBA sequence motifs may function in isolated form and have utility in the isolation and characterization of multi-ubiquitinylated species. Autophagy receptors such as p62/SQSTM1 and NBR1, which simultaneously bind both ubiquitin and autophagy-specific ubiquitin-like modifiers, LC3/GABARAP, provide a molecular link between ubiquitination and autophagy.

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