Ada-(Ahx)3-(Leu)3-vinylsulfone
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
Biomol | 暂无 | 暂无 | 现货 |
A new class of proteasome inhibitors, considerably extended in comparison with the commonly used fluorescent substrates and peptide-based inhibitors, has been prepared. Evaluation of these new compounds revealed a set of highly potent proteasome inhibitors that target all individual active subunits with comparable affinity, unlike the other inhibitors described to date. These compounds are more potent in living cells than their shorter peptide vinyl sulphone counterparts. Modification of the most active compound, adamantaneacetyl-(6-aminohexanoyl)3-(leucyl)3-vinylmethyl-sulphone itself capable of proteasome inhibition in living cells, afforded a new set of radio- and affinity labels.
Product Specification
Formula: C50H88N6O8S
MW: 932.6
Purity: ≥94% (HPLC)
Appearance: Off-white powder
Sequence: Ada-(Ahx)3-(Leu)3-vinyl sulfone
Solubility: Soluble in DMSO (<50mM)
Long Term Storage: -20°C
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途