Mdivi-1
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
Biomol | 暂无 | 暂无 | 现货 |
Mdivi-1 is a selective inhibitor of mitochondrial division in yeast and mammalian cells which acts via inhibiting the mitochondrial division dynamin. In cells, Mdivi-1 inhibits apoptosis by inhibiting mitochondrial outer membrane permeabilization. Mdivi-1 causes the rapid (<5 min) reversible and dose-dependent formation of net-like mitochondria in wild-type cells with an IC50= ~10µM. In yeast, time-lapse fluorescence microscopy revealed no detectable mitochondrial division after treatment with Mdivi-1.
It inhibits Dnm1 GTPase activity in a dose dependent manner with an estimated IC50 of 1-10µM but is not a general inhibitor of GTPases.
Product Specification
Formula: C15H10Cl2N2O2S
MW: 353.2
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 338967-87-6
Solubility: Soluble in DMSO (25mg/ml).
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途