Replaces Prod. #: ALX-350-119
Inhibitor of angiogenesis and endothelial cell proliferation. Specific inhibitor of methionine aminopeptidase type II (MetAP-II) by covalently modifying a conserved active-site histidine. Precursor to TNP-470. Exhibits antitumor activity in estrogen-induced pituitary adenoma. Antineoplastic. Anti-infective.
Product Specification
Alternative Name: Fumidil B, Fumadil B, TNP-470
Formula: C26H34O7
MW: 458.6
Purity: ≥95% (TLC)
Appearance: Off-white to light yellow solid.
CAS: 23110-15-8
MI: 14: 4286
Source/Host: Isolated from Aspergillus fumigatus.
Solubility: Soluble in DMSO (25mg/ml) or diluted aqueous bases; slightly soluble in methanol or other alcoholic solvents; insoluble in water.
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored at -20°C. Stock solutions are stable for up to 3 months at -20°C. Unstable in aqueous solutions with pH >9.0 or pH <5.0.
Hazard: HARMFUL.
Handling: Keep under inert gas.
Protect from light and oxygen.

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途