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WithaferinA

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A diterpene fungal metabolite that acts as reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at early S phase. Prolongs the half life of DNA methyltransferase. Specific inhibitor of DNA polymerase α and δ in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer.
Product Specification
Formula: C20H34O4
MW: 338.5
Purity: ≥98% (TLC)
Appearance: White to off-white solid.
CAS: 38966-21-1
MI: 14: 727
Solubility: Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.

 

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途