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Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
Product Specification
Alternative Name: 2-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide, Bisindolylmaleimide I
Formula: C25H24N4O2
MW: 412.5  
Purity: 98% (TLC)
Appearance: Red solid.
CAS: 133052-90-1
Solubility: Soluble in dimethyl formamide or DMSO (10mg/ml, warm to 40°C and vortex well). 
Shipping: AMBIENT
Long Term Storage: -20°C
Handling: Protect from light.

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