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Very potent protein kinase C (PKC) inhibitor with high selectivity for the PKC isotypes α and β. Inhibits PKCα (IC50=2.3nM) and PKCß1 (IC50=6.2nM) but has no effect on δ, ε or γ isotypes. Potent antagonist of HIV-1 induction.
Product Specification
Alternative Name: 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole
Formula: C24H18N4O
MW: 378.4
Purity: ≥95% (HPLC)
Appearance: Off-white to yellow solid.
CAS: 136194-77-9
Solubility: Soluble in DMSO (25mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stock solutions are stable for at least 3-4 months when  stored at -20°C.
Handling: Protect from light.

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