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DuP-697 is a highly selective and irreversible inhibitor of cyclooxygenase-2 (COX-2). (COX-2 IC50=10nM, COX-1 IC50=800nM). It is an orally effective anti-inflammatory, analgesic and antipyretic agent which is not ulcerogenic. Inhibition of COX-2 by DuP-697 and other inhibitors exacerbates ischemia-induced myocardial dysfunction in the rabbit. It inhibits angiogenesis and induces apoptosis in human endothelial cells.
Product Specification
Formula: C17H12BrFO2S2
MW: 411.3
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 88149-94-4
Solubility: Soluble in DMSO (10mg/ml) or 100% ethanol (5mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C

DuP-697信息由上海叶舟生物科技有限公司为您提供，如您想了解更多关于DuP-697报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途