ZM-447439
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
Biomol | 暂无 | 暂无 | 现货 |
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BML-EI373-0010 10 mg INQUIRE ZM-447439 is a potent and selective inhibitor of Aurora B kinase (IC50=50nM), Aurora A and C are inhibited at higher concentrations (IC50=1000nM and 250nM respectively). Other kinases such as Cdk1 and PLK1 are not inhibited (up to 10mM). Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail.
Product Specification
Formula: C29H31N5O4
MW: 513.6
Purity: ≥98% (TLC)
CAS: 331771-20-1
Solubility: Soluble in DMSO (25 mg/ml).
Shipping: AMBIENT
Long Term Storage: +20°C
Use/Stability: Store solutions at -20°C for up to 3 months.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途