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N-Acetyl-S-geranylgeranyl-L-cysteine

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Replaces Prod. #: ALX-290-008
AGGC specifically blocks methyl esterification of geranylgeranylated proteins such as Rab proteins. AGGC blocks receptor-mediated signal transduction in human neutrophils (IC50=4 µM). Induces insulin release from HIT-T15 cells by mimicking the action of Rab3A and inhibits β2-integrin-induced actin polymerization (IC50~45 nM) in neutrophils.
Product Specification
Formula: C25H41NO3S
MW: 435.7
Purity: ≥98% (TLC)
Appearance: Yellow viscous oil.
CAS: 139332-94-8
Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C

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