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Mastoparan

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Replaces Prod. #: ALX-162-001
Cell permeable, amphiphilic, mast cell degranulating tetradecapeptide. Stimulates glycogenolysis and phospholipase D2 (PLD2) activity. Alters G-proteins in brain membranes. Directly activates G proteins by a mechanism analogous to that of G protein-coupled receptors. Acts preferentially on Gi and Go rather than Gs. Stimulates exocytosis and phosphoinositide breakdown in a variety of cells. Inhibits calmodulin, and activates PLA2. Acts as a mitogen in Swiss 3T3 cells and stimulates pertussis toxin-sensitive arachidonate release without phosphoinositide breakdown.
Product Specification
Formula: C70H131N19O15
MW: 1478.9
Purity: ≥98% (HPLC)
Sequence: H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2
Formulation: Lyophilized.
CAS: 72093-21-1
Source/Host: Synthetic. Originally isolated from wasp venom (Vespula lewisii).
Solubility: Soluble in water (1 mg/ml) or 100% ethanol.
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途