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A potent, cell-permeable histone deacetylase (HDAC) inhibitor. Inhibits HDACs in maize, Physarum and chicken. IC50=30nM for E. tenella HDAC. Displays antiprotozoal and antineoplastic activity. Induces expression of the γ-globin gene in erythroid cells. Shows antimitogenic activities. Induces cell cycle arrest and apoptosis in tumor cells.
Product Specification
Alternative Name: Cyclo-(D-Pro-L-Ala-D-Ala-L-2-amino-8-oxo-9,10-epoxydecanoic acid)
Formula: C21H32N4O6
MW: 436.5
Purity: ≥ 98%
Appearance: White to off-white powder.
CAS: 83209-65-8
Solubility: Soluble in DMSO.
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Hazard: TOXIC.

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