ENMD-1068;BML-N110-0005原装正品,其它生化试剂

货号：BML-N110-0005
产地：Biomol
Selective PAR-2 antagonist. Dose dependently inhibits calcium signaling in Lewis lung carcinoma cells stimulated with a soluble peptide PAR-2 agonist or trypsin, but not with a soluble PAR-1 agonist. Does not inhibit platelet aggregation stimulated by thrombin suggesting that it does not inhibit PAR-3 or PAR-4 signaling. Reduces TNF-α and IL-1β production from rheumatoid arthritis synovial primary cell culture and reduces joint swelling in a carageenan/kaolin-injected mouse model.
Product Specification
Formula: C15H29N3O2 . HCl . H2O
MW: 283.3 . 36.5 . 18.0
Purity: ≥98% (TLC)
Appearance: White solid.
Solubility: Soluble in water (5mg/ml), DMSO (2.5mg/ml) or 100% ethanol (5mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Store solutions at -20°C for up to 3 months.
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