Ingenol3,20-dibenzoate大量原装,其它生化试剂

产地：Biomol
货号：BML-PE186-0001
BML-PE186-0001 1 mg
Ingenol is a diterpenoid related to phorbol. Activates protein kinase C (PKC) and competes with [3H]phorbol dibutyrate for binding to PKCα (Ki for binding=240 nM). Induces apoptosis. Anticancer agent. Shows potent antileukemic activity in the P388 mouse assay. Displays unusually high mouse ear inflammatory activity, even though the 20-hydroxy group is blocked with a benzoate ester. It appears likely that this high potency is due to metabolic cleavage of the 20-benzoate group, which releases the more potent ingenol 3-benzoate.
Product Specification
Alternative Name: IDB
Formula: C34H36O7
MW: 556.7
Purity: ≥97%
Appearance: Colorless oil.
CAS: 59086-90-7
Solubility: Soluble in DMSO (20mg/ml) or ethanol (20mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Hazard: HARMFUL.
MAY BE CARCINOGENIC.
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