Gliotoxin正品原装
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
暂无 | 暂无 | 暂无 | 现货 |
BML-PI129-0010 10 mg
BML-PI129-0002 2 mg
Immunomodulating mycotoxin which acts by blocking membrane thiol groups. Inhibits the chymotrypsin-like activity of the 20S proteasome in a non-competitive manner. Causes apoptotic cell death in macrophages and thymocytes. Induces Ca2+ release from intact rat liver mitochondria. Inhibits the activation of transcription factor NF-κB in response to a variety of stimuli in T and B cells. Displays anti-inflammatory activity in vivo. Antioxidant. Inhibitor of farnesyltransferase and geranylgeranyltransferase I.A negatve control analog is available (Prod. No. BML-L122).
Product Specification
Alternative Name: [3R-(3α, 5aβ,6β,10aα)]-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10a-epi-dithiopyrazino[1,2-a]indole-1,4-dione
Formula: C13H14N2O4S2
MW: 326.4
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 67-99-2
MI: 14: 4441
RTECS: KB4725000
Source/Host: Isolated from Gladiocladium fimbriatum.
Solubility: Soluble in DMSO or methanol (10mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stock solutions are stable for up to 3 months when stored at -20°C.
Hazard: TOXIC.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途