MDL-28170大量原装正品,其它生化试剂

BML-PI130-0050 50 mg
BML-PI130-0010 10 mg
A potent and selective cell permeable calpain inhibitor. Inhibits oxidative damage-induced apoptosis in PC12 cells and capsaicin-induced apoptosis in dorsal root ganglion neurons. It protects against anoxia in rat optic nerves and reduces neuronal damage in an animal model of global cerebral ischemia(50 mg/kg). In isolated hippocampal pyramidal neurons, it inhibits Ca2+-induced suppression of neurite outgrowth (complete inhibition at 20 µM). Calpain I Ki = 8 nM; Cathepsin B Ki = 24 nM in isolated enzyme assays.
IC50 = 0.3 µM in intact cell assay.
Product Specification
Alternative Name: Z-Val-Phe-CHO
Concentration: C22H26N2O4
MW: 382.5
Purity: ≥98% (TLC)
Appearance: White solid
Sequence: Z-Val-Phe-CHO
CAS: 88191-84-8
Solubility: Soluble in DMSO (200mM)
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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