AAK1 antibody  
Cat.#: 3788-1
Rabbit Monoclonal Antibody
Clone ID: EPR5127
Swiss Prot: Q2M2I8
Mol Weight: 95kDaSize: 100ul

Description
AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. It interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin (1).

Recommended Applications
WB, IHC

Applications and Recommended Dilution Factors
WB: 1:10,000 - 50,000
IHC: 1:50 - 100

Species Reactivity
Human, Mouse, Rat

*Cross reactivity with mouse determined by western blot and IHC.
Cross reactivity with rat determined by western blot only.

Products Data

Western blot analysis on (A) rat kidney, (B) 293T, (C) HepG2, and (D) NIH/3T3 cell lysates using anti-AAK1 RabMAb (cat. #3788-1). Specificity AsyntheticpeptidecorrespondingtoresiduesinhumanAAK1wasusedasanimmunogen. Storage Condition and BufferStore at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. Alternative NamesAAK1 antibody, DKFZp686F03202 antibody, DKFZp686K16132 antibody, FLJ23712 antibody, FLJ25931 antibody, FLJ31060 antibody, FLJ42882 antibody, FLJ45252 antibody, KIAA1048 antibody, MGC138170 antibody, MGC164568 antibody, MGC164570 antibody, AP2-associated protein kinase 1 antibody, Adaptor-associated kinase 1 antibody Description References1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8.

Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-AAK1 RabMAb (cat. #3788-1).

DescriptionAAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. It interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin (1).

Recommended ApplicationsWB, IHC

Applications and Recommended Dilution FactorsWB: 1:10,000 - 50,000
IHC: 1:50 - 100

Species Reactivity *Human, Mouse, Rat

*Cross reactivity with mouse determined by western blot and IHC.
Cross reactivity with rat determined by western blot only.

 

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途