Apolipoprotein L1(APOL1)antibody
Cat.#: 3245-1
Rabbit Monoclonal Antibody
Clone ID: EPR2907(2)
Swiss Prot: O14791
Mol Weight: 42kDa
Size: 100ul

Description
Apolipoprotein L1 is a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. Apolipoprotein L1 is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this protein (1).

Recommended Applications
WB, ICC, IP, FC

Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:100 - 250
IP: 1:10 - 100
FC: 1:10 - 100

Species Reactivity
Human

Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on (A) human plasma, (B) ovary cancer, and (C) HepG2 cell lysates using anti-Apolipoprotein L1 RabMAb (cat. #3245-1).

Specificity
A synthetic peptide corresponding to residues in human Apolipoprotein L1 was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
APOL1 antibody, APO-L antibody, APOL antibody, APOL-I antibody, FSGS4 antibody, Apolipoprotein L1 antibody, Apolipoprotein L-I antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8. 

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