ACTC Antibody(Center)
Cat.#: T1055
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P62736
Mol Weight: 42kDa
Size: 100ug

Description
ACTC belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this protein cause aortic aneurysm familial thoracic type 6.

Recommended Applications
WB, IHC, FC, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
IHC: 1:50~100
FC: 1:10~50
ELISA: 1:1,000

Species Reactivity
Human

Products Data 

 

Western blot analysis of ACTC antibody (Center) in K562 cell line lysates (35ug/lane). ACTC (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human skeletal muscle with ACTC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specificity
This ACTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197~227 amino acids from the Center region of human ACTC.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Alternative Names
ACTA2 antibody, AAT6 antibody, ACTSA antibody, Actin, aortic smooth muscle antibody, Alpha-actin-2 antibody, Cell growth-inhibiting gene 46 protein antibody

Description References
Guo,D.C., Papke,C.L. Am. J. Hum. Genet. 84 (5), 617-627 (2009)
Guo,D.C., Pannu,H. Nat. Genet. 39 (12), 1488-1493 (2007) 

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