ALDH5A1 antibody
Cat.#: S2075
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P51649
Mol Weight: 58.66kDa
Size: 100ug

Description
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data

Sample (30ug of whole cell lysate)
A: A431
7.5% SDS PAGE
diluted at 1:1000

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 85 and 334 of human ALDH5A1

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
ALDH5A1 antibody, SSADH antibody, SSDH antibody, Succinate-semialdehyde dehydrogenase, mitochondrial antibody, Aldehyde dehydrogenase family 5 member A1 antibody, NAD(+)-dependent succinic semialdehyde dehydrogenase antibody

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途