蛋白质/抗原/多肽
MouseAntiHumanVonHippel-LindauProtein(VHL)
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
Prospec | 暂无 | 暂无 | 现货 |
产品介绍
Catalogue Number | ANT-316 | |
Synonyms | Von Hippel-Lindau disease tumor suppressor, pVHL, Protein G7, VHL, RCA1, VHL1, HRCA1. | |
Type | Mouse Anti Human Monoclonal. | |
Introduction | Von Hippel-Lindau disease is a dominant inherited syndrome characterized by the predisposition to develop various kinds of benign and malignant tumors, including clear cell renal carcinomas, pheochromocytomas and hemangioblastomas of the central nervous system and retina. VHL syndrome is caused by germline mutation in the VHL tumor suppressor, and VHL tumors are associated with loss or mutation of the remaining wild-type allele. VHL has two domains: a roughly 100-residue NH2-terminal domain rich in sheet (-domain) and a smaller -helical domain (-domain), held together by two linkers and a polar interface. VHL protein is also involved in the degradation of hypoxia-inducible factor (HIF). | |
Clone | P52A11AT. | |
Immunogen | Anti-human VHL mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human VHL amino acids 1-154 purified from E. coli. | |
Ig Subclass | Mouse IgG2b heavy chain and κ light chain. | |
Purification Method | VHL antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
Protein formulation | 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. | |
Storage Procedures | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
Stability / Shelf Life | 12 months at -20°C. 1 month at 4°C. | |
Applications | VHL antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500. | |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | |
Related Products |
|
MouseAntiHumanVonHippel-LindauProtein(VHL)信息由上海希美生物科技有限公司为您提供,如您想了解更多关于MouseAntiHumanVonHippel-LindauProtein(VHL)报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途