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血管生成
Imiquimod
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| I129798-50mg | 99011-02-6 | 询价 |
| I129798-5g | 99011-02-6 | 询价 |
| I129798-500mg | 99011-02-6 | 询价 |
| I129798-1g | 99011-02-6 | 询价 |
| I129798-100mg | 99011-02-6 | 询价 |
产品介绍
- 分子式 C14H16N4
- 分子量240.31
- Beilstein号
- EC号 MFCD00866946
- MDL号 MFCD00866946
- PubChem编号 24724516
属性
| 熔点 | 297~299℃ |
| 溶解性 | Soluble in DMSO (4 mg/ml ,warming to 60 °C for 15 minutes) DMF (1.5 mg/ml) at 37 °C, and water (slightly soluble) at 37 °C. Insoluble in ethanol. |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A TLR7 activator and angiogenesis inhibitor. |
| 产品介绍 | |
| 生化机理 | Imiquimod is a derivative of imidazoquinolinamine that inhibits angiogenesis and is an immune response modifier. Studies have reported that Imiquimod has the ability to downregulate metastasis and induce alpha-interferon (IFN-α). Additionally, Imiquimod is a TLR7 (toll-like receptor 7) agonist which induces plasmacytoid dendritic cell (pDC) maturation. Imiquimod acts on dendritic cells expressing TLR7, and induces an immune response. Nuclear factor-B helps mediate the activity of Imiquimod, and is involved in increasing chemokine and cytokine levels. The antiangiogenic property of Imiquimod has been shown to be mediated by IL-18. Research shows that Imiquimod can induce apoptosis in cancer cells. Also suggested to be an activator of caspase-3 and NFκB. |
| 别名 | 咪喹莫特; 1-异丁基-1H-咪唑[4.5-C]喹啉-4-胺基;1-(2-甲基丙基)-4-氨基-1H-咪唑并[4,5-c]喹啉;Aldara; R 837; Zyclara;1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine;4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline;1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine |
Imiquimod信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Imiquimod报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途