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Minisite
血管生成
DMXAA (Vadimezan)
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
AI问答
配套的仪器设备?
可以搭配的相关耗材试剂?
产品参数
货号 | CAS号 | 操作 |
---|---|---|
D129922-100mg | 117570-53-3 | 询底价 |
D129922-5mg | 117570-53-3 | 询底价 |
D129922-250mg | 117570-53-3 | 询底价 |
D129922-25mg | 117570-53-3 | 询底价 |
产品介绍
- 分子式 C17H14O4
- 分子量282.29
- Beilstein号
- EC号
- MDL号 MFCD00870555
- PubChem编号
属性
溶解性 | Soluble in DMSO (>10 mg/ml), DMF (~14 mg/ml), 1:1 solution of DMF: PBS (pH=7.2) (~0.5 mg/ml), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). |
存贮条件 | 储存温度 2-8°C |
描述
应用 | 5,6-dimethylxanthenone-4-acetic acid (DMXAA) has been used to induce type-I IFN signaling in a stimulator of interferon genes (STING) dependent manner.It has also been used to study STING-dependent signaling in the absence of infection. |
产品介绍 | 5,6-dimethylxanthenone-4-acetic acid (DMXAA) is a flavone acetic acid derivative. It acts as a vascular disrupting agent (VDA), which damages tumor vasculature and stimulates an anti-tumor immune response. It stimulates hemorrhagic necrosis. |
备注 | DMXAA (Vadimezan) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM, respectively. Phase 3. |
生化机理 | DMXAA is an apoptosis inducer, and an anti-vascular. DMXAA is an inhibitor of NQO1, Flk-1 and Flt-1. |
别名 | ASA404; 5,6-MeXAA; NSC-640488;2,5-己酮可可碱; 5,6-二甲基呫吨酮-4-乙酸; 5,6-二甲基黄嘌呤-4-乙酸;5,6-Dimethylxanthenone-4-acetic Acid; ASA404; Vadimezan;5,6-MeXAA; NSC-640488 |
DMXAA (Vadimezan)信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于DMXAA (Vadimezan)报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途