诚信认证：
工商注册信息已核实！
Bardoxolone
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
| 货号 | CAS号 | 操作 |
|---|---|---|
| B125862-100mg | 218600-44-3 | 询价 |
| B125862-25mg | 218600-44-3 | 询价 |
属性
| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | Bardoxolone(RTA 402)是抗氧化炎症调节剂（AIM）的先导化合物，此类AIM是转录因子Nrf2诱导剂。 |
| 生化机理 |
Bardoxolone methyl, previously known as RTA 402, is the lead molecule in Reata's portfolio of Antioxidant Inflammation Modulators (AIMs). The AIMs are potent inducers of the transcription factor Nrf2, an important biological target that controls the production of many of the body's antioxidant and detoxification enzymes. Because oxidative stress and inflammation occur throughout the course of chronic kidney disease (CKD) and are known to contribute to loss of kidney function, agents that activate the Nrf2 pathway in patients with CKD may provide a novel method for preserving or improving kidney function. Bardoxolone methyl is currently being investigated as a potential oral once-a-day treatment for CKD. |
| 别名 | CDDO;RTA 401;RTA401;RTA-401;2-氰基-3,12-二氧代齐墩果-1,9-二烯-28-酸;CDDO;RTA 401;RTA401;RTA-401;2-Cyano-3,12-dioxooleana-1,9-dien-28-oic acid |
Bardoxolone信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Bardoxolone报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途