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10058-F4
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| F129209-25mg | 403811-55-2 | 询价 |
产品介绍
- 分子式 C12H11NOS2
- 分子量249.35
- Beilstein号
- EC号
- MDL号 MFCD00758517
- PubChem编号
属性
| 溶解性 | Soluble in DMSO: >10 mg/mL and Water: <2 mg/mL |
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | A c-Myc inhibitor and apoptosis inducer. |
| 产品介绍 | 10058-F4是一种c-Myc抑制剂，特异性抑制c-Myc-Max相互作用，且抑制c-Myc靶基因表达的转录激活。 |
| 备注 | 10058-F4 is a c-Myc inhibitor that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression. |
| 生化机理 | 10058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. c-Myc is a proto-oncogene that plays an important role in cell proliferation, differentiation, and apoptosis. 10058-F4 has been shown to arrest cell growth at G0/G1 phase. Experiments show that 10058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. c-Myc is a proto-oncogene that plays an important role in cell proliferation, differentiation, and apoptosis. 10058-F4 has been shown to arrest cell growth at G0/G1 phase. Experiments show that extended exposure to 10058-F4 causes apoptosis via upregulation of Bax, expression of cytoplasmic Cytochrome C, down-regulation of Bcl-2, and cleavage of caspase-3,-7, and -9. This compound has been found to also upregulate cyclin-dependent kinase inhibitors, p21 and p27. |
| 别名 | 5-[(4-乙基苯基)亚甲基]-2-硫代-4-噻唑烷酮;5-(4-乙基苯亚甲基)绕丹宁;5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
10058-F4信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于10058-F4报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途