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Minisite
G蛋白偶联受体&G蛋白
Alvimopan
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
A124975-100mg | 156053-89-3 | 询价 |
A124975-25mg | 156053-89-3 | 询价 |
A124975-5mg | 156053-89-3 | 询价 |
产品介绍
- 分子式 C25H32N2O4
- 分子量424.53
- Beilstein号
- EC号 MFCD09838268
- MDL号
- PubChem编号
属性
旋光率 | +46 to +52°, c = 1.0 in DMSO |
溶解性 | DMSO |
存贮条件 | 储存温度2-8℃ |
描述
应用 | A gastroprokinetic, peripheral μ-opioid receptor antagonist. |
产品介绍 | Alvimopan is a gastroprokinetic, peripheral-μ-opioid receptor antagonist. |
生化机理 | Alvimopan(ADL 8-2698; Entereg; LY 246736) is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, Alvimopan(ADL 8-2698; Entereg; LY 246736) binds to mu-opioid receptors in the gut, thereby reversing opiod-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone.A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. |
别名 | 爱维莫潘; 2-([(2S)-2-([(3R,4R)-4-(3-羟基苯基)-3,4-二甲基哌啶-1-基]甲基)-3-苯基丙酰]氨基)乙酸;ADL 8-2698; Entereg; LY 246736;2-([(2S)-2-([(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl)-3-phenylpropanoyl]amino)acetic acid |
Alvimopan信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于Alvimopan报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途