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Cinacalcet HCl
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| C129866-10mg | 364782-34-3 | 询价 |
| C129866-1g | 364782-34-3 | 询价 |
| C129866-250mg | 364782-34-3 | 询价 |
| C129866-5g | 364782-34-3 | 询价 |
| C129866-50mg | 364782-34-3 | 询价 |
产品介绍
- 分子式 C22H22F3N·HCl
- 分子量393.87
属性
| 溶解性 | Soluble in water (1 mg/ml at 25 °C), DMSO (79 mg/ml at 25 °C), ethanol (33 mg/ml at 25 °C), and methanol. |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | An allosteric activator of CaSR |
| 产品介绍 | Cinacalcet Hydrochloride is a type II calcimimetic agent which controls calcium levels in cells by allosteric activation of CaSR (calcium sensing receptors). Studies show that Cinacalcet Hydrochloride affects cell proliferation in CHO cells transfected with CaSRs. In addition, it is known that Cinacalcet Hydrochloride inhibits the secretion of the parathyroid hormone (PTH). These studies suggest that Cinacalcet Hydrochloride in instrumental in increasing the cytoplasmic concentration of Ca2+. Furthermore, Cinacalcet Hydrochloride is an analog of NPS R-568 which contains a much better metabolic profile. |
| 备注 | AMG-073 represents a new class of compounds for the treatment of hyperparathyroidism. |
| 生化机理 | AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism. |
| 别名 | Mimpara, Sensipar;(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride;盐酸西那卡塞;盐酸甲状旁腺激素;N-((1R)-1-(1-萘基)乙基)-3-(3-(三氟甲基)苯基)丙-1-胺盐酸盐 |
Cinacalcet HCl信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Cinacalcet HCl报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途