诚信认证：
工商注册信息已核实！
快速导航
产品分类
微信二维码
Minisite
QQ号咨询
G蛋白偶联受体&G蛋白
Phenoxybenzamine HCl
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| P129843-5g | 63-92-3 | 询价 |
| P129843-1g | 63-92-3 | 询价 |
| P129843-25g | 63-92-3 | 询价 |
产品介绍
- 分子式 C18H22ClNO·HCl
- 分子量340.3
- EC号 200-569-7
- MDL号 MFCD00055152
- PubChem编号 24277760
属性
| 溶解性 |
|
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | A non-specific irreversible adrenergic (AR) antagonist. |
| 产品介绍 | Phenoxybenzamine HCl是一种非选择性，不可逆α受体拮抗剂，IC50为550 nM。 |
| 备注 | Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM. |
| 生化机理 | Phenoxybenzamine is a cell-permeable, non-specific, irreversible AR (α-adrenergic) antagonist that also acts as an CaM inhibitor. Phenoxybenzamine inhibits calmodulin-stimulated phosphodiesterase activity. This product has been shown to inhibit cGMP accumulation in cerebellar cells evoked by an exogenous nitric oxide donor. Phenoxybenzamine has been used to generate a novel glucocorticoid receptor that complexes with HSP90, but has no hormone binding ability. This compound has also been employed to block high levels of catecholamines. |
| 别名 | 竹林胺;酚苄胺;苯氧苄胺;盐酸苯氧苄胺;N-(1-甲基-2-苯氧乙基)-N-(2-氯乙基)苯甲胺盐酸盐;Dibenzyline Hydrochloride;N-Phenoxyisopropyl-N-benzyl-2-chloroethylamine Hydrochloride;N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine Hydrochloride |
Phenoxybenzamine HCl信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Phenoxybenzamine HCl报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途