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G蛋白偶联受体&G蛋白
Anamorelin
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
A125440-50mg | 249921-19-5 | 询价 |
A125440-5mg | 249921-19-5 | 询价 |
A125440-10mg | 249921-19-5 | 询价 |
产品介绍
- 分子式 C31H42N6O3
- 分子量546.70
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
产品介绍 | Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. |
生化机理 |
Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. |
别名 | RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643;阿拉莫林; (3R)-1-(2-甲基丙氨酰-D-色氨酰)-3-苯甲基-3-哌啶 1,2,2-三甲基甲酰肼;RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643;(3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide |
Anamorelin信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于Anamorelin报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途