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Stattic
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| S129623-100mg | 19983-44-9 | 询底价 |
| S129623-25mg | 19983-44-9 | 询底价 |
产品介绍
- 分子式 C8H5NO4S
- 分子量211.19
属性
| 沸点 | 461.1° C |
| 熔点 | 129.80° C |
| 折光率 | 1.67 |
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
| 密度 | 1.6000 |
描述
| 应用 | An inhibitor of Stat3 activation |
| 产品介绍 | Stattic是STAT3的有效抑制剂，主要用于癌症的治疗。 |
| 备注 | Stattic, the first nonpeptidic small molecule, potently inhibits STAT3 activation and nuclear translocation with IC50 of 5.1 μM, highly selectivity over STAT1. |
| 生化机理 | Stat3 Inhibitor V, Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events. Stattic has been used as a tool for probing the upstream activation of this factor, significantly expressed in many cancer cell lines, and interruption of this pathway in breast cancer cell lines lead to an increased apoptotic rate in these cells. Stat3 Inhibitor V, Stattic is an inhibitor of Stat3. |
| 别名 | ;Stat three inhibitory compound:6-Nitrobenzo[b]thiophene-1,1-dioxide; 6-Nitrobenzo[b]thiophene-1,1-dioxide |
Stattic信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Stattic报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途