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离子通道
Cilnidipine
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| C125274-100g | 132203-70-4 | 询价 |
| C125274-1g | 132203-70-4 | 询价 |
| C125274-25g | 132203-70-4 | 询价 |
| C125274-5g | 132203-70-4 | 询价 |
产品介绍
- 分子式 C27H28N2O7
- 分子量492.52
- Beilstein号
- EC号 MFCD00865853
- MDL号 MFCD00865853
- PubChem编号 24892414
属性
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in DMSO (> 25 mg/ml), ethanol (20 mg/ml), water (≤ 2 mg/ml), and methanol. |
描述
| 应用 | An L-/N-type calcium channel protein inhibitor and blocker |
| 产品介绍 | Cilnidipine是一种钙离子通道抑制剂。It is a dual blocker of L-type voltage-gated calcium channels in vascular smooth muscle and N-type calcium channels in sympathetic nerve terminals that supply blood vessels. |
| 备注 | Cilnidipine is a calcium channel blocker. |
| 生化机理 | Cilnidipine is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity. Cilnidipine has displayed renal and vascular protective effects and improved baroreflex sensitivity in patients with hypertension. It has also demonstrated neuroprotective effects in a rat focal brain ischemia model by removing free radicals and activating the phosphatidylinositol 3-kinase pathway. |
| 别名 | FRC 8653;西尼地平;1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二羧酸2-甲氧基乙酯肉桂醇酯;FRC 8653;3-cinnamyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
Cilnidipine信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Cilnidipine报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途