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甲苯磺丁脲
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| T129578-100g | 64-77-7 | 询价 |
| T129578-10g | 64-77-7 | 询价 |
| T129578-1g | 64-77-7 | 询价 |
| T129578-250g | 64-77-7 | 询价 |
| T129578-25g | 64-77-7 | 询价 |
| T129578-500g | 64-77-7 | 询价 |
| T129578-5g | 64-77-7 | 询价 |
产品介绍
- 分子式
- 分子量270.35
- Beilstein号
- EC号
- MDL号 MFCD00027169
- PubChem编号
属性
| 溶解性 | Soluble in DMSO or 100% ethanol; insoluble in water. |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | Tolbutamide is a sulfonylurea agonist for secretion of insulin by beta-cells. In rat pancreatic beta-cells cultured in the presence of Tolbutamide displayed increased numbers of beta-cells in a dose responsive manner with beta-cell numbers doubling at 100 μg/ml of Tolbutamide. The compound displayed inhibitory action towards beta-cells at concentrations greater than 100 μg/ml. In addition in the presence of low glucose concentrations Tolbutamide’s cytotrophic action was inhibited. On isolated dog pancreas islets Tolbutamide at 180 μM stimulated the release of somatostatin, insulin and glucagon in the absence of glucose. in all situations the loss of Ca2+ eliminated all effects of Tolbutamide. The compound has been observed to mechanistically enhance the secretion of insulin by highly selective amplification of insulin secretory burst mass. |
| 别名 | 1-丁基-3-(4-甲苯磺酰基)脲;甲糖宁;1-Butyl-3-(4-methylphenylsulfonyl)urea |
甲苯磺丁脲信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于甲苯磺丁脲报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途