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Tariquidar
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| T126671-100mg | 206873-63-4 | 询底价 |
| T126671-10mg | 206873-63-4 | 询底价 |
| T126671-1mg | 206873-63-4 | 询底价 |
| T126671-50mg | 206873-63-4 | 询底价 |
产品介绍
- 分子式 C38H38N4O6
- 分子量646.73
- EC号 MFCD09837824
属性
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
描述
| 备注 | Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines. Phase 3. |
| 生化机理 |
Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. |
| 别名 | 3-Quinolinecarboxamide, N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-;3-Quinolinecarboxamide, N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]- |
Tariquidar信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Tariquidar报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途