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药物分子
Ferrostatin-1 (Fer-1)
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| F129882-25mg | 347174-05-4 | 询价 |
| F129882-5mg | 347174-05-4 | 询价 |
| F129882-100mg | 347174-05-4 | 询价 |
产品介绍
- 分子式 C15H22N2O2
- 分子量262.35
属性
| 溶解性 |
|
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | A potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis |
| 产品介绍 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. |
| 备注 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. |
| 生化机理 | Ferrostatin-1 (2 μM) prevents erastin-induced ferroptosis in cancer cells, as well as glutamate-induced cell death in postnatal rat brain slices. Ferrostatin-1 is a lipid ROS scavenger, with the N-cyclohexyl moiety serving as a lipo-philic anchor within biological membranes. Ferrostatin-1 Ferrostatin-1 is a potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis. Ferrostatin-1 prevents ferroptopic cell death in cancer cells and glutamate-induced toxicity in organotypic rat brain slices. It appears that Ferrostatin-1 controls lipid soluble ROS. |
| 别名 | ;3-Amino-4-cyclohexylaminobenzoic Acid Ethyl Ester; |
Ferrostatin-1 (Fer-1)信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Ferrostatin-1 (Fer-1)报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途