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药物分子
西洛他唑
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
C129678-250mg | 73963-72-1 | 询价 |
C129678-5g | 73963-72-1 | 询价 |
C129678-1g | 73963-72-1 | 询价 |
产品介绍
- 分子式 C20H27N5O2
- 分子量369.46
- Beilstein号
- EC号
- MDL号 MFCD00866780
- PubChem编号 24278291
属性
溶解性 |
|
存贮条件 | 储存温度2-8℃ |
描述
应用 | 三磷酸二酯酶(PDE 3)抑制剂,.抗血栓形成和强心剂 |
产品介绍 | Cilastazol is a 2-oxo-quinoline with vasodilator, antimitogenic, antithrombotic, and cardiotonic properties. This compound has been shown to cause inhibition of adenosine uptake, eventually resulting in changes to cAMP levels. Studies have shown Cilostazol to be a potent inhibitor of PDE3A (phosphodiesterase 3A) in the cardiovascular system. In addition Cilastazol has also been observed to inhibit mitogenesis, migration of vascular smooth muscle cells, and platelet aggregation. Cilostazol displays a capacity to lower levels of serum triglycerides and cause some increase in HDL-cholesterol levels. |
备注 | Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake. |
别名 | 6-[4-(1-环己基-1H-四唑-5-基)丁氧基]-3,4-二氢-2(1H)-喹啉酮;6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC 13013; OPC 21; Pletaal |
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途