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药物分子
TAK-700 (Orteronel)
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
T126788-1mg | 426219-18-3 | 询价 |
T126788-25mg | 426219-18-3 | 询价 |
T126788-5mg | 426219-18-3 | 询价 |
产品介绍
- 分子式 C18H17N3O2
- 分子量307.35
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
备注 | TAK-700 (Orteronel) is a potent and highly selective human 17,20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3. |
生化机理 |
TAK-700 is an oral, selective, non-steroidal androgen synthesis inhibitor of the 17,20 lyase, which is a key enzyme in the production of steroidal hormones. In preclinical studies, TAK-700 has been shown to bind to and inhibit the enzyme 17,20 lygase in both the testes and adrenal glands. TAK-700 is currently under clinical Phase III studies. |
别名 | (S)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-e]imidazol-7-yl)-N-methyl-2-naphthamide;(S)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-e]imidazol-7-yl)-N-methyl-2-naphthamide |
TAK-700 (Orteronel)信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于TAK-700 (Orteronel)报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途