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Trelagliptin
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
货号 | CAS号 | 操作 |
---|---|---|
T127446-100mg | 865759-25-7 | 询价 |
T127446-5mg | 865759-25-7 | 询价 |
T127446-10mg | 865759-25-7 | 询价 |
T127446-25mg | 865759-25-7 | 询价 |
T127446-50mg | 865759-25-7 | 询价 |
- 分子式 C18H20FN5O2
- 分子量357.38
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
产品介绍 | Trelagliptin 是高度选择性的长效的DPP-4抑制剂。 |
生化机理 |
Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-daily. A once-weekly treatment, such as trelagliptin, would provide patients with a convenient treatment alternative and has the potential to improve treatment compliance. |
别名 | SYR-472;SYR472;SYR 472;曲格列汀;SYR-472;SYR472;SYR 472;(R)-2-[[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]methyl]-4-fluorobenzonitrile |
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途