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微生物制剂
Emtricitabine
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| E125328-1g | 143491-57-0 | 询价 |
| E125328-250mg | 143491-57-0 | 询价 |
| E125328-25g | 143491-57-0 | 询价 |
| E125328-25mg | 143491-57-0 | 询价 |
| E125328-50mg | 143491-57-0 | 询价 |
| E125328-5g | 143491-57-0 | 询价 |
产品介绍
属性
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A HIV-1 reverse transcriptase (HIV-1 RT) inhibitor |
| 产品介绍 | Emtricitabine 是一种核苷逆转录酶抑制剂，IC50为27.7 μM |
| 备注 | Emtricitabine (Emtriva) is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM. |
| 生化机理 | Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reverse transcriptase manner. Studies indicate that the structure of Emtricitabine, specifically the unnatural β-L structural configuration produce greater antiviral effects in vitro on HIV and HBV than other antiviral agents. To activate Emtricitabine it needs to undergo multistep intracellular phosphorylation by various cellular kinases. These studies suggest that Emtricitabine competitively inhibits HIV-1 reverse transcriptase (HIV-1 RT) and can cause termination of DNA chain elongation in the virus via incorporation into the viral genome. |
| 别名 | 恩曲他滨;5-氟-1-(2R,5S)-[2-羟甲基-1,3-氧硫环-5-酰]胞嘧啶;依曲西他滨;盐酸恩曲他滨;恩曲他滨 EMTRIVA;恩曲他滨 EMTRICITABINE;Emtriva;Coviracil;BW1592;BW-1592;BW 1592;Atripla; |
Emtricitabine信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Emtricitabine报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途