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NBD-556
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| N125945-100mg | 333353-44-9 | 询价 |
| N125945-25mg | 333353-44-9 | 询价 |
| N125945-5mg | 333353-44-9 | 询价 |
产品介绍
- 分子式 C17H24ClN3O2
- 分子量337.84
属性
| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | NBD-556是CD4的小分子模拟物，能识别HIV-1包膜蛋白gp120。 |
| 生化机理 | NBD-556 N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamide analogs as a novel class of human immunodeficiency virus type 1 (HIV-1) entry inhibitors that block the gp120–CD4 interaction. Human immunodeficiency virus (HIV-1) interaction with the primary receptor, CD4, induces conformational changes in the viral envelope glycoproteins that allow binding to the CCR5 second receptor and virus entry into the host cell. The small molecule NBD-556 mimics CD4 by binding the gp120 exterior envelope glycoprotein, moderately inhibiting virus entry into CD4-expressing target cells and enhancing CCR5 binding and virus entry into CCR5-expressing cells lacking CD4. |
| 别名 | NBD 556;NBD556;N-(4-氯苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺;N1-(4-氯苯基)-N2-(2,2,6,6-四甲基-4-哌啶基)乙二酰胺;N1-(4-氯苯基)-N2-(2,2,6,6-四甲基哌啶-4-基)草酰胺;NBD 556;NBD556;N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide;N-(4-Chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide;N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide |
NBD-556信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于NBD-556报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途