诚信认证：
工商注册信息已核实！
快速导航
产品分类
微信二维码
Minisite
QQ号咨询
细胞信号转导
Atomoxetine HCl
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| A129721-1g | 82248-59-7,83015-26-3 | 询价 |
| A129721-250mg | 82248-59-7,83015-26-3 | 询价 |
| A129721-50mg | 82248-59-7,83015-26-3 | 询价 |
| A129721-5g | 82248-59-7,83015-26-3 | 询价 |
产品介绍
- 分子式 C17H21NO·HCl
- 分子量291.82
- Beilstein号
- EC号 200-659-6
- MDL号 MFCD06410992
- PubChem编号
属性
| 敏感性 | 对热和湿度敏感 |
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A selective SLC6A2 inhibitor. |
| 产品介绍 | Atomoxetine HCl是一种选择性的去甲肾上腺素(NE)转运体抑制剂，Ki为5 nM，作用于人体5-HT和DA转运体亲和力比其低15和290倍。 |
| 备注 | Atomoxetine is a selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM, with 15- and 290-fold lower affinity for human 5-HT and DA transporters.Phase 4. |
| 生化机理 | Tomoxetine hydrochloride (Atomoxetine, LY 139603) is a competitive and specific inhibitor of SLC6A2 while demonstrating weak ST and DAT inhibition as studied in synaptosomes of rat hypothalamus. Additionally, studies indicate that this (-) optical isomer is more effective than the (+) isomer, LY139602 (ent S-(+)-Atomoxetine Hydrochloride;). In the prefrontal cortex of rats, Tomoxetine was reported to not cause an increase in dopamine within the striatum or nucleus accumbens which may be useful in additional research studies investigating the reward pathways of the brain. Tomoxetine hydrochloride is an inhibitor of NMDA. |
| 别名 | 盐酸托莫西汀;盐酸阿托莫西汀; (R)-N-甲基-3-(2-甲基苯氧基)-3-苯丙基胺盐酸盐;(R)-Tomoxetine Hydrochloride;(R)-N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine Hydrochloride; LY 139603 |
Atomoxetine HCl信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Atomoxetine HCl报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途